期刊
INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING
卷 30, 期 11, 页码 1294-1313出版社
WILEY
DOI: 10.1002/cnm.2658
关键词
hemodynamics; boundary conditions; autoregulation; impedance; vascular trees
类别
资金
- National Science Foundation (NSF) [DMS-0636590]
- NSF East Asia and Pacific Summer Institutes (EAPSI) [1015642]
- Office Of The Director
- Office Of Internatl Science &Engineering [1015642] Funding Source: National Science Foundation
We discuss the implementation and calibration of a new generalized structured tree boundary condition for hemodynamics. The main idea is to approximate the impedance corresponding to the vessels downstream from a specific outlet. Unlike previous impedance conditions, the one considered here is applicable to general transient flows as opposed to periodic ones only. The physiological character of the approach significantly simplifies calibration. We also describe a novel way to incorporate autoregulation mechanisms in structured arterial trees at minimal computational cost. The strength of the approach is illustrated and validated on several examples through comparison with clinical data. Copyright (c) 2014 John Wiley & Sons, Ltd.
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