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ICOS gene haplotypes correlate with IL10 secretion and multiple sclerosis evolution
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IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
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The diabetes susceptibility locus Idd5.1 on mouse chromosome 1 regulates ICOS expression and modulates murine experimental autoimmune encephalomyelitis
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A co-stimulatory molecule on activated T cells, H4/ICOS, delivers specific signals in Th cells and regulates their responses
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The costimulatory molecule ICOS plays an important role in immunopathogenesis of EAE
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ICOS is critical for T helper cell-mediated lung mucosal inflammatory responses
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ICOS costimulation requires IL-2 and can be prevented by CTLA-4 engagement
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ICOS is essential for effective T-helper-cell responses
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Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells
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