期刊
INTERNATIONAL DAIRY JOURNAL
卷 20, 期 4, 页码 262-268出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.idairyj.2009.11.011
关键词
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资金
- North Carolina Dairy Foundation, Danisco USA
- Dairy Management Inc.
Recent research efforts have focused on understanding the interactions of probiotic bacteria with commensal gut bacteria and the human host as a means to determine mechanisms of probiotic functionality that contribute to their beneficial attributes. Our growing understanding of the intrinsic interactions between probiotic and commensal bacteria and between the milieu of bacteria and the host tissues of the gastrointestinal tract (GIT) has been facilitated by the use of 'omic' technologies. Surveys of bacterial inhabitants in the GIT using sequencing technologies have demonstrated the complexities of this human organ which varies between different populations and individuals, such as diet. In addition, transcriptomics have rapidly facilitated an insight into the complex communication between bacteria (commensal and probiotic) and the GIT. This review outlines the recent important advances in this exciting area of research, which has led to a greater understanding of the critical interface between gut microbiota, probiotic bacteria and the host. (C) 2009 Elsevier Ltd. All rights reserved.
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