Estimation for the heating effect of magnetic nanoparticles in perfused tissues

This work uses the transient bio-heat equation to predict the temperature rise behavior occurring in biological tissues during magnetic nanoparticles hyperthermia. A numerical scheme is proposed to solve the bio-heat transfer problem in a bi-layered spherical tissue with blood perfusion and metabolism. The analytical solution evidences the accuracy of the numerical scheme and examines the results in the literature. (C) 2008 Elsevier Ltd. All rights reserved.