期刊
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH
卷 84, 期 5, 页码 471-477出版社
SPRINGER
DOI: 10.1007/s00420-010-0575-6
关键词
Indium; Occupational exposure; Interstitial lung disease; KL-6; SP-D
资金
- Grants-in-Aid for Scientific Research [23249033] Funding Source: KAKEN
Purpose The present review is aimed to introduce an new occupational lung disease, Indium Lung. Methods We searched case reports and epidemiological studies concerning indium-related lung diseases and reviewed. Results Up to March, 2010, 7 cases of interstitial pneumonia in Japanese indium-exposed workers, two cases of pulmonary alveolar proteinosis (PAP) in US indium-exposed workers, one case of PAP in a Chinese indium-exposed worker, and 4 cross-sectional surveys in Japan had been published. All cases and epidemiological studies in Japan indicate that exposure to hardly soluble indium compounds causes interstitial as well as emphysematous lung damages, which we call Indium Lung. Based on the epidemiological studies, the Japan Society for Occupational Health proposed 3 mu g/l of indium in serum as an occupational exposure limit based on biological monitoring to prevent significant increase of KL-6. Comments Long-term follow-up of currently and formerly indium-exposed workers is essential not only to clarify the natural history of indium lung but also to trace the incidence of lung cancer. It is also necessary to elucidate the mechanism of indium lung and difference in clinical manifestations between Japanese and US cases.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据