期刊
INTERNAL MEDICINE JOURNAL
卷 42, 期 9, 页码 968-978出版社
WILEY
DOI: 10.1111/j.1445-5994.2012.02886.x
关键词
lupus; hydroxychloroquine; survival; cardiovascular disease; retinopathy
资金
- University of Melbourne
- St. Vincent's Hospital Melbourne Research Endowment Fund
- UCB Australia
- GSK Australia
Due to multiple beneficial effects, including control of disease activity, reduction in cardiovascular events and improved survival, hydroxychloroquine is now recommended long-term for all patients with systemic lupus erythematosus. However, patients must be made aware of the possible risk of retinal toxicity and have eye examinations to monitor for this complication. As hydroxychloroquine becomes more widely used in systemic lupus erythematosus, physicians must also be aware of rare but serious adverse effects, including neuromyotoxicity and cardiotoxicity.
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