期刊
INTENSIVE CARE MEDICINE
卷 35, 期 5, 页码 796-809出版社
SPRINGER
DOI: 10.1007/s00134-009-1396-5
关键词
Depression; Critical care; Risk factors; Quality of life; Outcome assessment (health care)
资金
- NHLBI NIH HHS [P050 HL73994] Funding Source: Medline
- NIMH NIH HHS [K23 MH64543] Funding Source: Medline
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [P50HL073994] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF MENTAL HEALTH [K23MH064543] Funding Source: NIH RePORTER
To critically review data on the prevalence of depressive symptoms in general intensive care unit (ICU) survivors, risk factors for these symptoms, and their impact on health-related quality of life (HRQOL). We conducted a systematic review using Medline, EMBASE, Cochrane Library, CINAHL, PsycINFO, and a hand-search of 13 journals. Fourteen studies were eligible. The median point prevalence of clinically significant depressive symptoms was 28% (total n = 1,213). Neither sex nor age were consistent risk factors for post-ICU depression, and severity of illness at ICU admission was consistently not a risk factor. Early post-ICU depressive symptoms were a strong risk factor for subsequent depressive symptoms. Post-ICU depressive symptoms were associated with substantially lower HRQOL. Depressive symptoms are common in general ICU survivors and negatively impact HRQOL. Future studies should address how factors related to individual patients, critical illness and post-ICU recovery are associated with depression in ICU survivors.
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