期刊
INTEGRATIVE BIOLOGY
卷 6, 期 12, 页码 1196-1200出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ib00210e
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资金
- National Research Foundation of Korea (NRF) - Ministry of Science, ICT & Future Planning [NRF-2013R1A1A1076126, NRF-2012M3A9C6050104]
- Next-Generation BioGreen 21 Program [PJ009986]
- Rural Development Administration, Republic of Korea
- National Research Foundation of Korea Grant - Korean Government (Ministry of Education, Science and Technology) [NRF-2011-357-C00100]
- National Research Foundation of Korea [357-2011-1-C00100, 2012M3A9C6050104] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
In most cases, induced pluripotent stem (iPS) cells must be maintained by replacing basic fibroblast growth factor (bFGF)-containing medium daily to inhibit spontaneous differentiation. However, complete inhibition of differentiation is difficult to achieve even with frequent replacement of medium because of bFGF instability. Here, we established a novel system for the sustained release of bFGF from a modified surface by using a nanofilm fabrication method.
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