相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。AIR signalling: more than meeting at the fork
Edward A. Nam et al.
BIOCHEMICAL JOURNAL (2011)
Processing of O-6-methylguanine into DNA double-strand breaks requires two rounds of replication whereas apoptosis is also induced in subsequent cell cycles
Steve Quiros et al.
CELL CYCLE (2010)
Multiple roles of ATM in monitoring and maintaining DNA integrity
Frederick A. Derheimer et al.
FEBS LETTERS (2010)
Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway
Yiyong Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
The DNA Damage Response: Making It Safe to Play with Knives
Alberto Ciccia et al.
MOLECULAR CELL (2010)
Blinded by the Light: The Growing Complexity of p53
Karen H. Vousden et al.
CELL (2009)
Brca2/Xrcc2 dependent HR, but not NHEJ, is required for protection against O-6-methylguanine triggered apoptosis, DSBs and chromosomal aberrations by a process leading to SCEs
Wynand P. Roos et al.
DNA REPAIR (2009)
The DNA-damage response in human biology and disease
Stephen P. Jackson et al.
NATURE (2009)
O6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo
Joanna Klapacz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Interplay of DNA repair pathways controls methylation damage toxicity in Saccharomyces cerevisiae
Petr Cejka et al.
GENETICS (2008)
ATR: an essential regulator of genome integrity
Karlene A. Cimprich et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
JNK signaling in apoptosis
D. N. Dhanasekaran et al.
ONCOGENE (2008)
Mismatch repair-dependent processing of methylation damage gives rise to persistent single-stranded gaps in newly replicated DNA
Nina Mojas et al.
GENES & DEVELOPMENT (2007)
The DNA damage response: Ten years after
J. Wade Harper et al.
MOLECULAR CELL (2007)
MGMT: Key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents
Bernd Kaina et al.
DNA REPAIR (2007)
An imperfect G2/M checkpoint contributes to chromosome instability following irradiation of S and G2 phase cells
Andrea Krempler et al.
CELL CYCLE (2007)
Structure of the human MutSα DNA lesion recognition complex
Joshua J. Warren et al.
MOLECULAR CELL (2007)
ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling
Thomas Stiff et al.
EMBO JOURNAL (2006)
Mismatch repair-dependent iterative excision at irreparable O6-methylguanine lesions in human nuclear extracts
Sally J. York et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
ATR kinase activation mediated by MutSα and MutLα in response to cytotoxic O6-methylguanine adducts
Ken-Ichi Yoshioka et al.
MOLECULAR CELL (2006)
Homologous recombination prevents methylation-induced toxicity in Escherichia coli
Anetta Nowosielska et al.
NUCLEIC ACIDS RESEARCH (2006)
Systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis
KA Janes et al.
SCIENCE (2005)
Characterization of the mismatch repair defect in the human lymphoblastold MT1 cells
M Szadkowski et al.
CANCER RESEARCH (2005)
Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2
AW Adamson et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation
IA Manke et al.
MOLECULAR CELL (2005)
Apoptotic signaling in response to a single type of DNA lesion, O6-methylguanine
MJ Hickman et al.
MOLECULAR CELL (2004)
MGMT: Its role in cancer aetiology and cancer therapeutics
SL Gerson
NATURE REVIEWS CANCER (2004)
An Msh2 point mutation uncouples DNA mismatch repair and apoptosis
DP Lin et al.
CANCER RESEARCH (2004)
Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility
GZ Yang et al.
CANCER CELL (2004)
Mechanisms and consequences of methylating agent-induced SCEs and chromosomal aberrations: a long road traveled and still a far way to go
B Kaina
CYTOGENETIC AND GENOME RESEARCH (2004)
Alkylation damage in DNA and RNA -: repair mechanisms and medical significance
F Drablos et al.
DNA REPAIR (2004)
Mismatch repair-dependent G2 checkpoint induced by low doses Of SN1 type methylating agents requires the ATR kinase
L Stojic et al.
GENES & DEVELOPMENT (2004)
MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation
Y Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Roles of MGMT and MLH1 proteins in alkylation-induced apoptosis and mutagenesis
Y Takagi et al.
DNA REPAIR (2003)
Chk1 and Chk2 kinases in checkpoint control and cancer
J Bartek et al.
CANCER CELL (2003)
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
CJ Bakkenist et al.
NATURE (2003)
The mismatch repair system is required for S-phase checkpoint activation
KD Brown et al.
NATURE GENETICS (2003)
O-6-alkylguanine-DNA alkyltransferase: role in carcinogenesis and chemotherapy
GP Margison et al.
BIOESSAYS (2002)
Genome maintenance mechanisms for preventing cancer
JHJ Hoeijmakers
NATURE (2001)
The DNA damage response: putting checkpoints in perspective
BBS Zhou et al.
NATURE (2000)
Repair of O6-alkylguanine by alkyltransferases
AE Pegg
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2000)
Mutation in the magnesium binding site of hMSH6 disables the hMutSα sliding clamp from translocating along DNA
I Iaccarino et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)