期刊
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
卷 39, 期 4, 页码 245-253出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.ibmb.2009.01.008
关键词
Melanization; Dopa decarboxylase; Phenoloxidase; Ecdysone; Juvenile hormone; Transcription factor; Manduca; Nuclear receptor
资金
- Japan Society for the Promotion of Science [17380033]
- Program for Promotion of Basic Research Activities for Innovative Biosciences (PROBRAIN)
- USDA [2001-35302-10918]
- Grants-in-Aid for Scientific Research [17380033] Funding Source: KAKEN
Many insect developmental color changes are known to be regulated by both ecdysone and juvenile hormone. Yet the molecular mechanisms underlying this regulation have not been well understood. This review highlights the hormonal mechanisms involved in the regulation of two key enzymes [dopa decarboxylase (DDC) and phenoloxidase] necessary for insect cuticular melanization, and the molecular action of 20-hydroxyecdysone on various transcription factors leading to DDC expression at the end of a larval molt in Manduca sexta. In addition, the ecdysone cascade found in M. sexta is compared with that of other organisms. (C) 2009 Elsevier Ltd. All rights reserved.
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