期刊
INORGANICA CHIMICA ACTA
卷 362, 期 3, 页码 811-819出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.ica.2008.02.039
关键词
Platinum; Azide; Photochemistry; Crystal structure; Anticancer
The synthesis and characterisation of eight new octahedral Pt-IV complexes of the type trans, trans, trans-[Pt(N-3)(2)(OH)(2)(NH3)(Am)] where Am = methylamine (2), ethylamine (4), thiazole (6), 2-picoline (8), 3-picoline (10), 4-picoline (12), cyclohexylamine (14), and quinoline (16) are reported, including the X-ray crystal structures of complexes 2, 8, and 14 as well as that of two of the precursor Pt-II complexes (trans-[ Pt(N-3)(2)(NH3)(methylamine)] (1) and trans-[Pt(N-3)(2)(NH3)(cyclohexylamine)](13)). Irradiation with UVA light rapidly induces loss in intensity of the azide-to-Pt-IV charge-transfer bands and gives rise to photoreduction of platinum. These complexes have potential for use as photoactivated anticancer agents. (C) 2008 Elsevier B. V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据