Efficient palladium-catalyzed Suzuki cross-coupling reaction with β-ketoamine ligands

A series of beta-ketoamine ligands with different steric and electronic substituents on the backbone and with aniline moieties have been synthesized and characterized. In the presence of PdCl2, catalytic studies indicated that they are effective ligands for Suzuki cross-coupling of various aryl bromides with phenylboronic acid, under aerobic conditions. (C) 2011 Elsevier B.V. All rights reserved.