An unexpected oxovanadium(IV) complex with in situ generated lactone ligand: Synthesis, crystal structure and DNA-binding property

A novel unexpected oxovanadium(IV) complex, [VO(L)(Phen)] (H(2)L=2-((2-hydroxynaphthalen-1-yl)-methyleneamino)-5-oxotetrahydrofuran-2-carboxylic acid, Phen = 1, 10-phenanthroline) (1), in which the L(2-) is an unexpected in situ generated lactone Schiff base ligand from the precursor of K(2)HL(1) (K(2)HL(1) = potassium 2-(((2-hydroxynaphthalen-1-yl)methylene)amino)pentanedioate), has been synthesized and structurally characterized. The DNA binding properties of 1 with calf thymus DNA (CT-DNA) have been investigated by fluorescence and circular dichroism (CD) spectra, results indicate that 1 can bind to CT-DNA via an intercalative mode. (C) 2010 Elsevier B.V. All rights reserved.