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Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I
Michaela Ulrike Gack et al.
CELL HOST & MICROBE (2009)
Phosphorylation of the influenza A virus protein PB1-F2 by PKC is crucial for apoptosis promoting functions in monocytes
David Mitzner et al.
CELLULAR MICROBIOLOGY (2009)
The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA
Irving C. Allen et al.
IMMUNITY (2009)
The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1
Paul G. Thomas et al.
IMMUNITY (2009)
The functional impairment of natural killer cells during influenza virus infection
Hailong Guo et al.
IMMUNOLOGY AND CELL BIOLOGY (2009)
Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice
Arash Shahangian et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8
Dipyaman Ganguly et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Inflammasome recognition of influenza virus is essential for adaptive immune responses
Takeshi Ichinohe et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Interactions of α-, β-, and θ-Defensins with Influenza A Virus and Surfactant Protein D
Mona Doss et al.
JOURNAL OF IMMUNOLOGY (2009)
Neutrophils Ameliorate Lung Injury and the Development of Severe Disease during Influenza Infection
Michelle D. Tate et al.
JOURNAL OF IMMUNOLOGY (2009)
Critical Role of IL-17RA in Immunopathology of Influenza Infection
Christopher R. Crowe et al.
JOURNAL OF IMMUNOLOGY (2009)
IL-10 Deficiency Unleashes an Influenza-Specific Th17 Response and Enhances Survival against High-Dose Challenge
K. Kai McKinstry et al.
JOURNAL OF IMMUNOLOGY (2009)
Differentiated Human Alveolar Type II Cells Secrete Antiviral IL-29 (IFN-λ1) in Response to Influenza A Infection
Jieru Wang et al.
JOURNAL OF IMMUNOLOGY (2009)
Protective Role for Protease-Activated Receptor-2 against Influenza Virus Pathogenesis via an IFN-γ-Dependent Pathway
Khaled Khoufache et al.
JOURNAL OF IMMUNOLOGY (2009)
Human defensins activate monocyte-derived dendritic cells, promote the production of proinflammatory cytokines, and up-regulate the surface expression of CD91
Pietro Presicce et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2009)
The NS1 Protein of the 1918 Pandemic Influenza Virus Blocks Host Interferon and Lipid Metabolism Pathways
Rosalind Billharz et al.
JOURNAL OF VIROLOGY (2009)
Influenza Virus Directly Infects Human Natural Killer Cells and Induces Cell Apoptosis
Huawei Mao et al.
JOURNAL OF VIROLOGY (2009)
Eukaryotic Stress Granules: The Ins and Outs of Translation
J. Ross Buchan et al.
MOLECULAR CELL (2009)
Immunodeficiency Associated with FCN3 Mutation and Ficolin-3 Deficiency
Lea Munthe-Fog et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Hospitalized Patients with 2009 H1N1 Influenza in the United States, April-June 2009.
Seema Jain et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
The Role of Antimicrobial Peptides at the Ocular Surface
Alison M. McDermott
OPHTHALMIC RESEARCH (2009)
Augmented Lung Inflammation Protects against Influenza A Pneumonia
Michael J. Tuvim et al.
PLOS ONE (2009)
Increased Susceptibility for Superinfection with Streptococcus pneumoniae during Influenza Virus Infection Is Not Caused by TLR7-Mediated Lymphopenia
Sabine Stegemann et al.
PLOS ONE (2009)
TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection
Jerry R. Aldridge et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Multiple components contribute to ability of saliva to inhibit influenza viruses
M. R. White et al.
ORAL MICROBIOLOGY AND IMMUNOLOGY (2009)
Critical role for cross-linking of trimeric lectin domains of surfactant protein D in antiviral activity against influenza A virus
Tesfaldet Tecle et al.
BIOCHEMICAL JOURNAL (2008)
Identification of oxidative stress and toll-like receptor 4 signaling as a key pathway of acute lung injury
Yumiko Imai et al.
CELL (2008)
P bodies, stress granules, and viral life cycles
Carla J. Beckham et al.
CELL HOST & MICROBE (2008)
The proapoptotic influenza A virus protein PB1-F2 regulates viral polymerase activity by interaction with the PB1 protein
Igor Mazur et al.
CELLULAR MICROBIOLOGY (2008)
MDA5/RIG-I and virus recognition
Osamu Takeuchi et al.
CURRENT OPINION IN IMMUNOLOGY (2008)
Innate immunity to influenza virus: implications for future therapy
Mitchell R. White et al.
EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2008)
Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory influenza infection
Arnaud Didierlaurent et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
The multifunctional NS1 protein of influenza A viruses
Benjamin G. Hale et al.
JOURNAL OF GENERAL VIROLOGY (2008)
Leukotriene B4 induces release of antimicrobial peptides in lungs of virally infected mice
Eric Gaudreault et al.
JOURNAL OF IMMUNOLOGY (2008)
Systemic release of high mobility group box 1 protein during severe murine influenza
Lisa M. Alleva et al.
JOURNAL OF IMMUNOLOGY (2008)
Antiviral activity of the long chain pentraxin PTX3 against influenza viruses
Patrick C. Reading et al.
JOURNAL OF IMMUNOLOGY (2008)
Airway epithelial versus immune cell Stat1 function for innate defense against respiratory viral infection
Laurie P. Shornick et al.
JOURNAL OF IMMUNOLOGY (2008)
CCR2+ monocyte-derived dendritic cells and exudate macrophages produce influenza-induced pulmonary immune pathology and mortality
Kaifeng Lisa Lin et al.
JOURNAL OF IMMUNOLOGY (2008)
Hyperinduction of cyclooxygenase-2-mediated proinflammatory cascade: A mechanism for the pathogenesis of avian influenza H5N1 infection
Suki M. Y. Lee et al.
JOURNAL OF INFECTIOUS DISEASES (2008)
Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: Implications for pandemic influenza preparedness
David M. Morens et al.
JOURNAL OF INFECTIOUS DISEASES (2008)
Alveolar macrophages are indispensable for controlling influenza viruses in lungs of pigs
Heui Man Kim et al.
JOURNAL OF VIROLOGY (2008)
Influenza A virus strains differ in sensitivity to the antiviral action of Mx-GTPase
Jan Dittmann et al.
JOURNAL OF VIROLOGY (2008)
Differential response of respiratory dendritic cell subsets to influenza virus infection
Xueli Hao et al.
JOURNAL OF VIROLOGY (2008)
Inhibition of pulmonary antibacterial defense by interferon-γ during recovery from influenza infection
Keer Sun et al.
NATURE MEDICINE (2008)
Update on Avian Influenza A (H5N1) Virus Infection in Humans
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Influenza-associated pediatric mortality in the United States:: Increase of Staphylococcus aureus coinfection
Lyn Finelli et al.
PEDIATRICS (2008)
Elevated levels of high mobility group box chromosomal protein-1 (HMGB-1) in sera from patients with severe bacterial pneumonia coinfected with influenza virus
Kosuke Kosai et al.
SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES (2008)
S-Nitrosylation of Surfactant Protein-D Controls Inflammatory Function
Chang-Jiang Guo et al.
PLOS BIOLOGY (2008)
Interferon-λ contributes to innate immunity of mice against influenza a virus but not against hepatotropic viruses
Markus Mordstein et al.
PLOS PATHOGENS (2008)
Chronic obstructive pulmonary disease and inhaled steroids alter surfactant protein D (SP-D) levels: a cross-sectional study
Michael W. Sims et al.
RESPIRATORY RESEARCH (2008)
Role of viral hemagglutinin glycosylation in anti-influenza activities of recombinant surfactant protein D
Kevan L. Hartshorn et al.
RESPIRATORY RESEARCH (2008)
Impact of neutrophils on antiviral activity of human bronchoalveolar lavage fluid
Mitchell R. White et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2007)
High susceptibility of human dendritic cells to avian influenza H5N1 virus infection and protection by IFN-α and TLR Ligands
Arunee Thitithanyanont et al.
JOURNAL OF IMMUNOLOGY (2007)
Expression of the 1918 influenza A virus PB1-F2 enhances the pathogenesis of viral and secondary bacterial pneumonia
Julie L. McAuley et al.
CELL HOST & MICROBE (2007)
Emerging role of dendritic cells in respiratory viral infection
Mitchell H. Grayson et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2007)
A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence
Gina M. Conenello et al.
PLOS PATHOGENS (2007)
α-defensin inhibits influenza virus replication by cell-mediated mechanism(s)
Mirella Salvatore et al.
JOURNAL OF INFECTIOUS DISEASES (2007)
Differential type I interferon induction by respiratory syncytial virus and influenza A virus in vivo
Nancy A. Jewell et al.
JOURNAL OF VIROLOGY (2007)
Increased survival after gemfibrozil treatment of severe mouse influenza
Alison Budd et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2007)
Control of apoptosis in influenza virus-infected cells by up-regulation of Akt and p53 signaling
Oleg P. Zhirnov et al.
APOPTOSIS (2007)
The interferon-inducible protein viperin inhibits influenza virus release by perturbing lipid rafts
Xiuyan Wang et al.
CELL HOST & MICROBE (2007)
Controls for lung dendritic cell maturation and migration during respiratory viral infection
Mitchell H. Grayson et al.
JOURNAL OF IMMUNOLOGY (2007)
Inhibition of the cytokine response does not protect against lethal H5N1 influenza infection
Rachelle Salomon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Acetylsalicylic acid (ASA) blocks influenza virus propagation via its NF-κB-inhibiting activity
Igor Mazur et al.
CELLULAR MICROBIOLOGY (2007)
Human neutrophil defensins increase neutrophil uptake of influenza A virus and bacteria and modify virus-induced respiratory burst responses
Tesfaldet Tecle et al.
JOURNAL OF IMMUNOLOGY (2007)
Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses
Christina Ehrhardt et al.
JOURNAL OF VIROLOGY (2007)
Natural antibody and complement mediate neutralization of influenza virus in the absence of prior immunity
Jerome P. Jayasekera et al.
JOURNAL OF VIROLOGY (2007)
Cutting edge: Influenza A virus activates TLR3-dependent inflammatory and RIG-1-dependent antiviral responses in human lung epithelial cells
Ronan Le Goffic et al.
JOURNAL OF IMMUNOLOGY (2007)
Evidence for phagocytosis of influenza virus-infected, apoptotic cells by neutrophils and macrophages in mice
Yumi Hashimoto et al.
JOURNAL OF IMMUNOLOGY (2007)
Reduced influenza viral neutralizing activity of natural human trimers of surfactant protein D
Kevan L. Hartshorn et al.
RESPIRATORY RESEARCH (2007)
Surfactant protein D in Pseudomonas aeruginosa keratitis
C. C. McCormick et al.
OCULAR IMMUNOLOGY AND INFLAMMATION (2007)
The immunoregulatory roles of lung surfactant collectins SP-A, and SP-D, in allergen-induced airway inflammation
Jiu-Yao Wang et al.
IMMUNOBIOLOGY (2007)
Both influenza-induced neutrophil dysfunction and neutrophil-independent mechanisms contribute to increased susceptibility to a secondary Streptococcus pneumoniae infection
Lynnelle A. McNamee et al.
INFECTION AND IMMUNITY (2006)
Flavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognition
Jennifer P. Wang et al.
JOURNAL OF IMMUNOLOGY (2006)
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates
Andreas Pichlmair et al.
SCIENCE (2006)
Influenza A virus NS1 protein binds p85β and activates phosphatidylinositol-3-kinase signaling
Benjamin G. Hale et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Correction of pulmonary abnormalities in Sftpd-/- mice requires the collagenous domain of surfactant protein D
Paul S. Kingma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Influenza virus evades innate and adaptive immunity via the NS1 protein
Ana Fernandez-Sesma et al.
JOURNAL OF VIROLOGY (2006)
Innate defense against influenza A virus: Activity of human neutrophil defensins and interactions of defensins with surfactant protein D
Kevan L. Hartshorn et al.
JOURNAL OF IMMUNOLOGY (2006)
A missense mutation of the Toll-like receptor 3 gene in a patient with influenza-associated encephalopathy
F Hidaka et al.
CLINICAL IMMUNOLOGY (2006)
Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1
R Gazit et al.
NATURE IMMUNOLOGY (2006)
Upon viral exposure, myeloid and plasmacytoid dendritic cells produce 3 waves of distinct chemokines to recruit immune effectors
B Piqueras et al.
BLOOD (2006)
The mannose-binding lectin: a prototypic pattern recognition molecule
K Takahashi et al.
CURRENT OPINION IN IMMUNOLOGY (2006)
Salivary agglutinin and lung scavenger receptor cysteine-rich glycoprotein 340 have broad anti-influenza activities and interactions with surfactant protein D that vary according to donor source and sialylation
KL Hartshorn et al.
BIOCHEMICAL JOURNAL (2006)
An absence of reactive oxygen species improves the resolution of lung influenza infection
Robert J. Snelgrove et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2006)
Detrimental contribution of the Toll-like receptor (TLR)3 to influenza A virus-induced acute pneumonia
Ronan Le Goffic et al.
PLOS PATHOGENS (2006)
Pathogenicity of influenza viruses with genes from the 1918 pandemic virus:: Functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice
TM Tumpey et al.
JOURNAL OF VIROLOGY (2005)
Augmentation of fatality of influenza in mice by inhibition of phagocytosis
Y Watanabe et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Association between mannose-binding lectin gene polymorphisms and susceptibility to severe acute respiratory syndrome coronavirus infection
HX Zhang et al.
JOURNAL OF INFECTIOUS DISEASES (2005)
Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1
Dmitriy Zamarin et al.
PLOS PATHOGENS (2005)
Influenza virus infection increases p53 activity: Role of p53 in cell death and viral replication
E Turpin et al.
JOURNAL OF VIROLOGY (2005)
Activation of the aryl hydrocarbon receptor increases pulmonary neutrophilia and diminishes host resistance to influenza A virus
S Teske et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2005)
Cooperative anti-influenza activities of respiratory innate immune proteins and neuraminidase inhibitor
MR White et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2005)
Interleukin-1 is responsible for acute lung immunopathology but increases survival of respiratory influenza virus infection
N Schmitz et al.
JOURNAL OF VIROLOGY (2005)
Surfactant protein D is present in human tear fluid and the cornea and inhibits epithelial cell invasion by Pseudomonas aeruginosa
M Ni et al.
INFECTION AND IMMUNITY (2005)
Involvement of toll-like receptor 3 in the immune response of lung evithelial cells to double-stranded RNA and influenza A virus
L Guillot et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
A common polymorphism in the SFTPD gene influences assembly, function, and concentration of surfactant protein D
R Leth-Larsen et al.
JOURNAL OF IMMUNOLOGY (2005)
Immunoregulatory functions of surfactant proteins
JR Wright
NATURE REVIEWS IMMUNOLOGY (2005)
Influenza A mutant viruses with altered NS1 protein function provoke caspase-1 activation in primary human macrophages, resulting in fast apoptosis and release of high levels of interleukins 1 beta and 18
J Stasakova et al.
JOURNAL OF GENERAL VIROLOGY (2005)
Effective targeting of pathogens to neutrophils via chimeric surfactant protein D/anti-CD89 protein
PJ Tacken et al.
JOURNAL OF IMMUNOLOGY (2004)
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
SS Diebold et al.
SCIENCE (2004)
Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing
WX Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Altered expression and in vivo lung function of protease-activated receptors during influenza A virus infection in mice
RS Lan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2004)
The cationic antimicrobial peptide LL-37 modulates dendritic cell differentiation and dendritic cell-induced T cell polarization
DJ Davidson et al.
JOURNAL OF IMMUNOLOGY (2004)
Pulmonary collectins modulate strain-specific influenza A virus infection and host responses
S Hawgood et al.
JOURNAL OF VIROLOGY (2004)
NF-κB-dependent induction of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas/FasL is crucial for efficient influenza virus propagation
WJ Wurzer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Neutrophil serine proteinases inactivate surfactant protein D by cleaving within a conserved subregion of the carbohydrate recognition domain
TO Hirche et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Interactions of influenza A virus with sialic acids present on porcine surfactant protein D
M van Eijk et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2004)
A recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of beta interferon and is attenuated in mice
NR Donelan et al.
JOURNAL OF VIROLOGY (2003)
By binding SIRPα or calreticulin/CD91, lung collectins act as dual function surveillance molecules to suppress or enhance inflammation
SJ Gardai et al.
CELL (2003)
Bronchoalveolar lavage fluid surfactant protein-A and surfactant protein-D are inversely related to inflammation in early cystic fibrosis
TL Noah et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2003)
Porcine pulmonary collectins show distinct interactions with influenza A viruses:: Role of the N-linked oligosaccharides in the carbohydrate recognition domain
M van Eijk et al.
JOURNAL OF IMMUNOLOGY (2003)
Caspase 3 activation is essential for efficient influenza virus propagation
WJ Wurzer et al.
EMBO JOURNAL (2003)
Lung and salivary scavenger receptor glycoprotein-340 contribute to the host defense against influenza A viruses
KL Hartshorn et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2003)
Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease?
CY Cheung et al.
LANCET (2002)
Distinctive anti-influenza properties of recombinant collectin 43
KL Hartshorn et al.
BIOCHEMICAL JOURNAL (2002)
Porcine surfactant protein D is N-glycosylated in its carbohydrate recognition domain and is assembled into differently charged oligomers
M van Eijk et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2002)
Surfactant protein-A-deficient mice display an exaggerated early inflammatory response to a beta-resistant strain of influenza A virus
G Li et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2002)
Absence of SP-A modulates innate and adaptive defense responses to pulmonary influenza infection
AM LeVine et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2002)
Surfactant protein D enhances clearance of influenza A virus from the lung in vivo
AM LeVine et al.
JOURNAL OF IMMUNOLOGY (2001)
Increased antiviral and opsonic activity of a highly multimerized collectin chimera
MR White et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Inhibition of interferon-mediated antiviral responses by influenza A viruses and other negative-strand RNA viruses
A García-Sastre
VIROLOGY (2001)
Enhanced antiviral and opsonic activity of a human mannose-binding lectin and surfactant protein D chimera
MR White et al.
JOURNAL OF IMMUNOLOGY (2000)
HMG1 protein stimulates DNA end joining by promoting association of DNA molecules via their ends
M Stros et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)
Type IIFN modulates innate and specific antiviral immunity
JE Durbin et al.
JOURNAL OF IMMUNOLOGY (2000)
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