期刊
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
卷 41, 期 2, 页码 128-132出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.injury.2009.01.001
关键词
Hydroxyapatite; External fixation; Pin loosening; Pin track infection
Objective: The primary objective of this systematic review of published randomised controlled trials was to evaluate whether there was a clinical benefit in terms of pin loosening and pin track infection, or deep infection, associated with hydroxyapatite coating of external fixator pins. The secondary objective was to evaluate whether there was a clinical benefit in terms of loss of alignment or malunion associated with hydroxyapatite coating of external fixator pins. Methods: Studies included were identified by a PubMed search for relevant randomised controlled trials on the 20th of December 2007. A systematic review was performed. Results: All of the studies concluded that there was significantly less pin loosening in the HA-coated groups although the definition of loosening was based on different criteria. However, there was insufficient evidence to properly evaluate the clinical benefit in terms of the numbers needed to treat to avoid premature pin removal. There was also insufficient evidence to evaluate whether any clinical benefit is gained by using HA-coated pins with respect to deep infection and malunion. Conclusion: A well designed large randomised controlled trial is required to determine the numbers needed to treat with HA-coated pins to reduce the incidence of clinically relevant pin loosening, axial deformity and pin track or deep infection. (C) 2009 Elsevier Ltd. All rights reserved
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