期刊
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
卷 40, 期 2, 页码 158-162出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.injury.2008.06.025
关键词
Fracture healing; Platelet; Un-united fracture
资金
- National Institute for Health Research [ACF-2006-08-001] Funding Source: researchfish
Platelet-rich plasma has been shown in several in vitro and animal Studies to play a role in promoting new bone formation. A systematic literature review was Conducted to identify the Current relevant evidence base, searching across multiple sources including Medline, Embase and the Cochrane Library, and finding five Clinically relevant articles. Only one was a randomised controlled trial, but thiS was Underpowered for the outcome measure defined. Three studies exclusively concerned children, and included those with congenital limb deformities. Two other reports were case series. Early clinical results suggest that the use platelet-rich plasma is safe and feasible, but that at present there is no clinical evidence of benefit in of p either acute or delayed fracture healing. (C) 2008 Elsevier Ltd. All lights reserved.
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