4.4 Article

Perspectives on articular cartilage biology and osteoarthritis

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ELSEVIER SCI LTD
DOI: 10.1016/j.injury.2008.01.044

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cartilage; extracellular matrix; chondrocyte metabolism; tissue engineering; pharmacology; osteoarthritis

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Cartilage biochemistry and cell biology is presented in context with osteoarthritis and cartilage regeneration and repair. Success in current efforts towards cell-based orthopaedic treatment options in cases of cartilage trauma and early stages of osteoarthritic degeneration will strictly depend on strategies that rely on known mechanisms of a chondrocyte's regulation.

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