期刊
INHALATION TOXICOLOGY
卷 24, 期 12, 页码 850-857出版社
INFORMA HEALTHCARE
DOI: 10.3109/08958378.2012.724728
关键词
E-cigarette; e-cig; ecigarette; ecig; emissions; vaping; nicotine vaporizer; SHS; secondhand vapor; SHV; eliquid; e-liquid; vapor; TSNA; VOC; PAH; DEG; PG; carbonyl; glycerine; cancer risk; risk estimate; exposure assessment; tobacco smoke; risk assessment; toxicity; indoor air quality; inhalation
类别
资金
- NVC
Context: Electronic cigarettes (e-cigarettes) have earned considerable attention recently as an alternative to smoking tobacco, but uncertainties about their impact on health and indoor air quality have resulted in proposals for bans on indoor e-cigarette use. Objective: To assess potential health impacts relating to the use of e-cigarettes, a series of studies were conducted using e-cigarettes and standard tobacco cigarettes. Methods and materials: Four different high nicotine e-liquids were vaporized in two sets of experiments by generic 2-piece e-cigarettes to collect emissions and assess indoor air concentrations of common tobacco smoke by products. Tobacco cigarette smoke tests were conducted for comparison. Results: Comparisons of pollutant concentrations were made between e-cigarette vapor and tobacco smoke samples. Pollutants included VOCs, carbonyls, PAHs, nicotine, TSNAs, and glycols. From these results, risk analyses were conducted based on dilution into a 40 m(3) room and standard toxicological data. Non-cancer risk analysis revealed No Significant Risk of harm to human health for vapor samples from e-liquids (A-D). In contrast, for tobacco smoke most findings markedly exceeded risk limits indicating a condition of Significant Risk of harm to human health. With regard to cancer risk analysis, no vapor sample from e-liquids A-D exceeded the risk limit for either children or adults. The tobacco smoke sample approached the risk limits for adult exposure. Conclusions: For all byproducts measured, electronic cigarettes produce very small exposures relative to tobacco cigarettes. The study indicates no apparent risk to human health from e-cigarette emissions based on the compounds analyzed.
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