期刊
INFLUENZA AND OTHER RESPIRATORY VIRUSES
卷 8, 期 1, 页码 25-32出版社
WILEY
DOI: 10.1111/irv.12156
关键词
BMI; influenza; obesity
Background Obesity was recognized as in independent risk factor for influenza during the 2009 H1N1 influenza pandemic. Objectives We evaluated the association between body mass index (BMI) and influenza-like illness (ILI) during two non-pandemic influenza seasons (2003-2004 and 2004-2005) and during the spring and fall waves of the 2009 H1N1 pandemic. Methods Adults with severe (inpatient) and mild (outpatient) ILI were compared to those without ILI using a case-cohort design. The study was nested among those insured by a single health insurance company, receiving care from a large multispecialty practice. Data were collected from insurance claims and the electronic health record. The primary exposure was obesity (BMI300kg/m(2)). Results Across three seasons, the crude and adjusted ORs for obesity and severe ILI were 165 (95% CI 131, 208) and 123 (95% CI 097, 157), respectively. An association was observed for those aged 20-59years (adjusted OR 192, 95% CI 126, 290), but not for those 60 and older (adjusted OR 108, 95% CI 080, 146). The adjusted ORs for obesity and severe ILI in 2003-2004, 2004-2005, and during H1N1 were 114 (95% CI 080, 164), 124 (95% CI 086, 179), and 176 (95% CI 091, 342), respectively. Among those with a Charlson Comorbidity Index score of zero, the adjusted ORs for 2003-2004, 2004-2005, and H1N1 were 160 (95% CI 093, 276), 143 (95% CI 080, 256), and 190 (95% CI 068, 527), respectively. Conclusions Our results suggest a small to moderate association between obesity and hospitalized ILI among adults.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据