期刊
INFLUENZA AND OTHER RESPIRATORY VIRUSES
卷 6, 期 4, 页码 245-256出版社
WILEY-BLACKWELL
DOI: 10.1111/j.1750-2659.2011.00304.x
关键词
Influenza; NA activity; NA antigenicity; NA inhibitors; neuraminidase
资金
- National Institute for Allergy and Infectious Diseases [AI50933, N01-AI50026, AI62950]
- NIGMS Consortium for Functional Glycomics [GM62116]
- Oklahoma Center for Advancement of Science and Technology
Please cite this paper as: Air. (2012) Influenza neuraminidase. Influenza and Other Respiratory Viruses 6(4), 245256. Influenza neuraminidase is the target of two licensed antivirals that have been very successful, with several more in development. However, neuraminidase has been largely ignored as a vaccine target despite evidence that inclusion of neuraminidase in the subunit vaccine gives increased protection. This article describes current knowledge on the structure, enzyme activity, and antigenic significance of neuraminidase.
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