期刊
INFLUENZA AND OTHER RESPIRATORY VIRUSES
卷 2, 期 6, 页码 229-235出版社
WILEY
DOI: 10.1111/j.1750-2659.2008.00060.x
关键词
Influenza vaccine; influenza; human; adjuvants; immunologic; intradermal injections
Challenges facing seasonal and pandemic influenza vaccination include: increasing the immunogenicity of seasonal vaccines for the most vulnerable, increasing vaccination coverage against seasonal influenza, and developing vaccines against pandemic strains that are immunogenic with very low quantities of antigen to maximize the number of people who can be vaccinated with a finite production capacity. We review Sanofi Pasteur's epidemic and pandemic influenza research and development programmes with emphasis on two key projects: intradermal influenza vaccine for seasonal vaccination of both elderly and younger adults, and pandemic influenza vaccine.
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