期刊
INFLAMMATORY BOWEL DISEASES
卷 16, 期 1, 页码 152-174出版社
OXFORD UNIV PRESS INC
DOI: 10.1002/ibd.20991
关键词
autophagy; Crohn's disease; bacterial infection; systems biology; mucosal immunology
资金
- National Institutes of Health (NIH) [A1062773, DK83756, DK043351]
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R01AI062773] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [R01DK083756, P30DK043351] Funding Source: NIH RePORTER
Autophagy is a conserved homeostatic process by which cells degrade and recycle cytoplasmic contents and organelles. Recently, autophagy has come to prominence as a factor in many disease states, including inflammatory bowel diseases. In this review we explore the recent discoveries in autophagy and how these relate to the special conditions experienced by the gut mucosa. We will pay particular attention to autophagy as an innate immune process and its role in the development and education of the adaptive immune system.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据