期刊
INFLAMMATION
卷 38, 期 1, 页码 218-223出版社
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10753-014-0025-9
关键词
asymmetric dimethylarginine; systemic sclerosis; nitric oxide; arginine
资金
- Key Project of the Education Department of Anhui Province Natural Science Research [KJ2012A165, KJ2014A127]
- Anhui Provincial Natural Science Foundation [1308085MH169]
Systemic sclerosis (SSc) is a kind of autoimmune disease characterized by inflammatory and endothelial dysfunction. Asymmetric dimethylarginine (ADMA), as an endogenous nitric oxide synthase inhibitor, can cause or contribute to the inflammatory syndrome and endothelial dysfunction. Recently, increased ADMA levels have been demonstrated in SSc, revealing that ADMA might play an important role for the associated manifestations of SSc. Besides, ADMA may play a significant role in the level of NO, which is produced by arginine. In the review, we discuss the role of arginine and ADMA in patients with SSc.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据