期刊
INFECTIOUS DISEASE CLINICS OF NORTH AMERICA
卷 24, 期 4, 页码 899-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.idc.2010.07.004
关键词
Hepatitis B; Hepatitis C; Pathogenesis; Liver transplantation; Transarterial chemoembolization; Radiofrequency ablation
资金
- National Institutes of Health [CA100882]
Hepatocellular carcinoma (HCC) is a major world health problem because of the high incidence and case fatality rate. In most patients, the diagnosis of HCC is made at an advanced stage, which limits the application of curative treatments. Most HCCs develop in patients with underlying chronic liver disease. Chronic viral hepatitis B and C are the major causes of liver cirrhosis and HCC. Recent improvements in treatment of viral hepatitis and in methods for surveillance and therapy for HCC have contributed to better survival of patients with HCC. This article reviews the epidemiology, cause, prevention, clinical manifestations, surveillance, diagnosis, and treatment approach for HCC.
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