4.2 Article

Respiratory Infections Due to Drug-Resistant Bacteria

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W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.idc.2010.04.007

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Community-acquired pneumonia; Hospital-acquired pneumonia; Antimicrobial resistance; Epidemiology; Clinical impact; Treatment guidelines

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Pneumonia is the most common infection that is the leading cause of death. The increasing antimicrobial resistance in major respiratory pathogens such as Streptococcus pneumoniae, Staphylococcus aureus and gram-negative bacteria has severely restricted the treatment options. Respiratory infections caused by multidrug-resistant bacteria are associated with a greater likelihood of inappropriate antimicrobial therapy and poor clinical outcome. Especially, treatment of infections caused by pandrug-resistant gram-negative bacteria is a major challenge. Continuous efforts to control the global spread of drug-resistant bacteria are essential.

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