期刊
INFECTION GENETICS AND EVOLUTION
卷 11, 期 7, 页码 1545-1563出版社
ELSEVIER
DOI: 10.1016/j.meegid.2011.07.022
关键词
Borrelia burgdorferi; Evolution; Molecular ecology; Ixodes; Multilocus sequence typing; MLST
资金
- Wellcome Trust [074322/Z/04/Z]
- Public Health Agency of Canada
- NIH-NIAID [AR041511, 5R21AI065848-03]
- USDA-ARS
- G. Harold and Leila Y. Mathers Charitable Foundation
- US Centers for Disease Control and Prevention
In order to understand the population structure and dynamics of bacterial microorganisms, typing systems that accurately reflect the phylogenetic and evolutionary relationship of the agents are required. Over the past 15 years multilocus sequence typing schemes have replaced single locus approaches, giving novel insights into phylogenetic and evolutionary relationships of many bacterial species and facilitating taxonomy. Since 2004, several schemes using multiple loci have been developed to better understand the taxonomy, phylogeny and evolution of Lyme borreliosis spirochetes and in this paper we have reviewed and summarized the progress that has been made for this important group of vector-borne zoonotic bacteria. (C) 2011 Elsevier B.V. All rights reserved.
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