期刊
INFECTION
卷 39, 期 5, 页码 467-471出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s15010-011-0128-2
关键词
Extended-spectrum beta-lactamase; Fecal carriage; Urinary tract infection; Carrier
资金
- Ministry of Education, Culture, Sports, Science and Technology, Japan
- Grants-in-Aid for Scientific Research [23590505] Funding Source: KAKEN
Introduction The current increase in the incidence of urinary tract infections (UTIs) worldwide caused by extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli may be due to the high number of ESBL-producing Enterobacteriaceae carriers in the community. However, whether ESBL-producing bacteria can cause UTIs in carriers remains uncertain. Materials and methods In this study, 21 fecal carriers of ESBL-producing Enterobacteriaceae were assessed for UTIs caused by ESBL-producing E. coli. Bacterial isolates obtained from patients' urine and stool specimens were phenotypically and genotypically examined. Clonal similarities of isolates were assessed by multilocus sequence typing (MLST) and random amplified polymorphic DNA (RAPD) fingerprinting. Results The study revealed that 9 of 21 carriers developed UTIs, and genetic analysis showed that 44% of the UTIs developed were caused by the same ESBL-producing E. coli as that found in the feces of the patients. Conclusions The ESBL-producing E. coli in carriers can cause UTIs.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据