期刊
INDUSTRIAL CROPS AND PRODUCTS
卷 42, 期 -, 页码 520-526出版社
ELSEVIER
DOI: 10.1016/j.indcrop.2012.06.045
关键词
Podophyllotoxin; Acyloxy; E-ring modification; Semisynthesis; Insecticidal activity
资金
- National Natural Science Foundation of China [31071737]
- Fok Ying Tong Education Foundation for Young Talents [121032]
- Program for Changjiang Scholars and Innovative Research Team in University [IRT1035]
- Special Funds of Central Colleges Basic Scientific Research Operating Expenses [QN2009045]
In continuation of our program aimed at the discovery and development of natural products-based insecticidal agents, a series of novel phenazine derivatives of 4 beta-acyloxypodophyllotoxin modified in the E-ring were synthesized, and preliminarily evaluated for their insecticidal activity against the pre-third-instar larvae of Mythimna separata Walker in vivo. Among all the derivatives, compounds 7b, 7g, 7h and 7j exhibited more pronounced insecticidal activity than or comparable to toosendanin. Especially compounds 7h and 7j displayed the best promising insecticidal activity. Meanwhile, the relationships between their structures and the insecticidal activity were also described. (C) 2012 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据