期刊
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
卷 52, 期 31, 页码 10802-10808出版社
AMER CHEMICAL SOC
DOI: 10.1021/ie401180t
关键词
-
资金
- Novartis-MIT Center for Continuous Manufacturing
- DARPA [N66001-11-C-4147]
We describe the development and application of an improved, membrane-based, liquid-liquid separator. Membrane-based separation relies on the exploitation of surface forces and the use of a membrane wetted by one of the phases; however, successful separation requires accurate control of pressures, making the operation and implementation cumbersome. Here we present an improved separator design that integrates a pressure control element to ensure that adequate operating conditions are always maintained. Additionally, the integrated pressure control decouples the separator from downstream unit operations. A detailed examination of the controlling physical equations shows how to design the device to allow operation across a wide range of conditions. Easy to implement, multistage separations such as solvent swaps and countercurrent extractions are demonstrated. The presented design significantly simplifies applications ranging from multistep synthesis to complex multistage separations.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据