4.6 Article

Fe3O4/poly(N-Isopropylacrylamide)/Chitosan Composite Microspheres with Multiresponsive Properties

期刊

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
卷 47, 期 20, 页码 7700-7706

出版社

AMER CHEMICAL SOC
DOI: 10.1021/ie800824q

关键词

-

资金

  1. National Nature Science Foundation of China [50573063]
  2. Program for New Century Excellent Talents in University
  3. Doctoral Program of Higher Education [2005038401]
  4. Xiamen University [0000X071C1]

向作者/读者索取更多资源

Muitiresponsive composite microspheres were fabricated via emulsion polymerization in two steps. Fe3O4 nanoparticles modified by oleic acid (about 13 nm in diameter) were first prepared, and then they were embedded in biocompatible chitosan (CS) and N-isopropylacrylamide (NIPAm). Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and thermogravimetric analysis (TGA) examined the structure and morphology of the composite microspheres. Scanning electron microscopy (SEM) and transmission electronic microscopy (TEM) indicate the diameter of the composite microspheres to be about 400 nm. The magnetic, thermo, and pH-sensitive properties of the composite microspheres were investigated. Magnetic measurements with magnet and superconducting quantum interference device (SQUID) reveal that the composite microspheres are superparamagnetic. The electromagnetically induced heating shows that the composite microspheres could be heated up to 45 degrees C in an alternating electromagnetic field. The dynamic light scattering (DLS) results confirm the thermoresponsive and pH-responsive properties. It was found that the lower critical solution temperature (LCST) of the composite microspheres is 29 degrees C in water, and the LCST changed from 28 to 32 degrees C in the pH range from 4.7 to 7.4. These composite microspheres with the multiresponsive properties show great promise in biomedical applications.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据