4.2 Article

Antiinflammatory Activity of Piper longum Fruit Oil

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INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES
卷 71, 期 4, 页码 454-U179

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WOLTERS KLUWER MEDKNOW PUBLICATIONS
DOI: 10.4103/0250-474X.57300

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Piper longum; antiinflammatory activity; rat hind paw edema method; carrageenan

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In the present study, antiinflammatory activity of the Piper longum dried fruit's oil was studied in rats using the carrageenan-induced right hind paw edema method. The activity was compared with that of standard drug ibuprofen. The dried fruit's oil inhibited carrageenan-induced rat paw edema. The results indicated that the dried fruit's oil produced significant (p<0.001) antiinflammatory activity when compared with the standard and untreated control.

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