期刊
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
卷 33, 期 3, 页码 515-518出版社
TAYLOR & FRANCIS LTD
DOI: 10.3109/08923973.2010.543907
关键词
Aedes aegypti; Ficus carica L.; milky sap; immunotoxicity effects; furocoumarins
资金
- ARPC
Ficus carica L., its fruits are delicious and can be eaten by human. Its leaves are commonly used to cure hemorrhoid and clear away heart ache. The milky sap of F. carica have a significant toxic effect against early fourth-stage larvae of Aedes aegypti L with an lethal concentration (LC50) value of 10.2 mu g/ml and an LC90 value of 42.3 mu g/ml. Two natural furocoumarins, 5-methoxypsoralen and 8-methoxypsoralen were isolated from the milky sap of F. carica. The LC50 value of 5-methoxypsoralen and 8-methoxypsoralen were 9.4 and 56.3 mu g/ml, respectively. The above indicates that major compounds may play a more important role in the toxicity of the milky sap of F. carica.
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