期刊
IMMUNOLOGY
卷 140, 期 1, 页码 22-30出版社
WILEY
DOI: 10.1111/imm.12117
关键词
dendritic cells; haematology; therapy/immunotherapy
类别
资金
- Leukaemia and Lymphoma Research
- Wellcome Trust
- Bright Red
Dendritic cells are highly adapted to their role of presenting antigen and directing immune responses. Developmental studies indicate that DCs originate independently from monocytes and tissue macrophages. Emerging evidence also suggests that distinct subsets of DCs have intrinsic differences that lead to functional specialisation in the generation of immunity. Comparative studies are now allowing many of these properties to be more fully understood in the context of human immunology.
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