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注意:仅列出部分参考文献,下载原文获取全部文献信息。Targeting phosphoinositide 3-kinase - Moving towards therapy
Romina Marone et al.
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Selective regulation of CD8 effector T cell migration by the p110γ isoform of phosphatidylinositol 3-kinase
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ICOS ligation recruits the p50α PI3K regulatory subunit to the immunological synapse
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FOXO1 regulates L-selectin and a network of human T cell homing molecules downstream of phosphatidylinositol 3-kinase
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Glucose uptake is limiting in T cell activation and requires CD28-mediated akt-dependent and independent pathways
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Tissue- and stimulus-dependent role of phosphatidylinositol 3-kinase Isoforms for neutrophil recruitment induced by chemoattractants in vivo
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Cutting edge: Atypical PKCs regulate T lymphocyte polarity and scanning behavior
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Class IA phosphoinositide 3-kinase modulates basal lymphocyte motility in the lymph node
Melanie P. Matheu et al.
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Impaired trafficking of Gnai2+/- and Gnai2-/- T lymphocytes:: Implications for T cell movement within lymph nodes
Il-Young Hwang et al.
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Requirements for T lymphocyte migration in explanted lymph nodes
Julie H. Huang et al.
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Basal B cell receptor-directed phosphatidylinositol 3-kinase signaling turns off RAGs and promotes B cell-positive selection
Laurent Verkoczy et al.
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Requirement for phosphoinositide 3-kinase p110δ signaling in B cell antigen receptor-mediated antigen presentation
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The p85α regulatory subunit of class IA phosphoinositide 3-kinase regulates β-selection in thymocyte development
Fumiko Shiroki et al.
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Cutting edge:: The phosphoinositide 3-kinase p110δ is critical for the function of CD4+CD25+Foxp3+ regulatory T cells
Daniel T. Patton et al.
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The p110δ isoform of phosphoinositide 3-kinase controls clonal expansion and differentiation of Th cells
Klaus Okkenhaug et al.
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FOXO transcription factors cooperate with δEF1 to activate growth suppressive genes in B lymphocytes
Jing Chen et al.
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B cells productively engage soluble antigen-pulsed dendritic cells: Visualization of live-cell dynamics of B cell dendritic cell interactions
NN Huang et al.
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Cutting edge:: T cell development requires the combined activities of the p110γ and p110δ catalytic isoforms of phosphatidylinositol 3-kinase
LMC Webb et al.
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Stable activation of phosphatidylinositol 3-kinase in the T cell immunological synapse stimulates Akt signaling to FoxO1 nuclear exclusion and cell growth control
S Fabre et al.
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Coligation of the B cell receptor with complement receptor type 2 (CR2/CD21) using its natural ligand C3dg: Activation without engagement of an inhibitory signaling pathway
T Lyubchenko et al.
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Phosphatidylinositol 3-kinase regulates thymic exit
SD Barbee et al.
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Vav-dependent and Vav-independent phosphatidylinositol 3-kinase activation in murine B cells determined by the nature of the stimulus
E Vigorito et al.
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Cutting edge:: Differential roles for phosphoinositide 3-kinases, p110γ and p110δ, in lymphocyte chemotaxis and homing
K Reif et al.
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Cutting edge: CD28-Mediated transcriptional and posttranscriptional regulation of IL-2 expression are controlled through different signaling pathways
M Sanchez-Lockhart et al.
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Tec kinase migrates to the T cell-APC interface independently of its pleckstrin homology domain
F Garçon et al.
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Enhanced T cell proliferation in mice lacking the p85β subunit of phosphoinositide 3-kinase
JA Deane et al.
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Proliferation and survival of activated B cells requires sustained antigen receptor engagement and phosphoinositide 3-kinase activation
AC Donahue et al.
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Cutting edge:: Distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL
JS Burr et al.
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