期刊
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL
卷 61, 期 11, 页码 1824-1834出版社
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TUFFC.2014.006543
关键词
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资金
- Pontificia Universidad Catolica del Peru [DGI 2013-0131]
- Institut National des Sciences Appliquees de Lyon (INSA-Lyon)
- program Investissements d'Avenir [ANR-10-LABX-0060, ANR-10-LABX-0063, ANR-11-IDEX-0007]
- Agence Nationale de la Recherche (ANR) [ANR-10-LABX-0060, ANR-10-LABX-0063] Funding Source: Agence Nationale de la Recherche (ANR)
Quantitative ultrasound (QUS) based on back-scatter coefficient (BSC) estimation has shown potential for tissue characterization. Beamforming using plane wave compounding has advantages for echographic, Doppler, and elastographic imaging; however, to date, plane wave compounding has not been experimentally evaluated for the purpose of BSC estimation. In this study, two BSC-derived parameters (i.e., the BSC midband fit and intercept) were estimated from experimental data obtained using compound plane wave beamforming. For comparison, QUS parameters were also estimated from data obtained using both fixed focus and dynamic receive beamforming. An ultrasound imaging system equipped with a 9-MHz center frequency, 64-element array was used to collect data up to a depth of 45 mm. Two gelatin phantoms with randomly distributed 20-mu m inclusions with a homogeneous scatterer concentration and a two-region scatterer concentration were used for assessing the precision and lateral resolution of QUS imaging, respectively. The use of plane wave compounding resulted in accurate QUS estimation (i.e., bias in the BSC parameters of less than 2 dB) and relatively constant lateral resolution (i.e., BSC midband fit 10% to 90% rise distance ranging between 1.0 and 1.5 mm) throughout a 45 mm field of view. Although both fixed focus and dynamic receive beamforming provided the same performance around the focal depth, the reduction in SNR away from the focus resulted in a reduced field of view in the homogeneous phantom (i.e., only 28 mm). The lateral resolution also degraded away from the focus, with up to a 2-fold and 10-fold increase in the rise distance at 20 mm beyond the focal depth for dynamic receive and fixed focus beamforming, respectively. These results suggest that plane wave compounding has the potential to improve the performance of spectral-based quantitative ultrasound over other conventional beamforming strategies.
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