期刊
MATERIALS LETTERS
卷 148, 期 -, 页码 163-166出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.matlet.2015.02.070
关键词
Polyphosphate; Regenerative medicine; SaOS-2 cells; Morphogenetic activity; Tissue engineering
资金
- ERC Advanced Investigator Grant [268476 BIOSILICA]
- European Commission [604036, 286059, 268476, 311848]
- International Human Frontier Science Program
Polyphosphate [polyP] has been proven to elicit morphogenetic activity on bone cells. By applying mild reaction conditions, a Ca-polyP material that displays a hardness of approximate to 1.3 GPa has been fabricated. The Ca-polyP granules are prone to hydrolytic degradation during in vitro incubation of the cells, suggesting that this property is associated with the observed bioactivity. (C) 2015 Elsevier B.V. All rights reserved.
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