期刊
MATERIALS LETTERS
卷 142, 期 -, 页码 180-183出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.matlet.2014.11.118
关键词
Electrospinning; 3D scaffold; Porosity gradient; Honeycomb structure; Nanofibers
资金
- Agence Nationale de la Recherche (NeoTissage) of France [ANR-P2N 2011 NANO 018-01]
A novel strategy to prepare thick nanofibrous scaffolds with controlled pore size and graded porosity by electrospinning was developed. Taking advantage of the self-assembling properties of bimodal nanofibers, it was possible to grow columns of pores with mm height. The use of a honeycomb microstructured collector allows the control of the pore diameter from 80 to 360 mu m. With increasing sample thickness, the columns of pores begin to merge creating a gradient in pore diameter of up to several hundreds of microns. These scaffolds should be ideal for tissue engineering applications. (C) 2014 Elsevier B.V. All rights reserved.
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