期刊
MATERIALS LETTERS
卷 139, 期 -, 页码 22-25出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.matlet.2014.10.042
关键词
Hydrothermal synthesis; NaYF4; Nanoparticles; Luminescence; Biological label
资金
- Chongqing Education Committee Science and Technology [KJ120617]
- Chongqing Education Science
A prerequisite for biomedical applications of rare-earth upconverting nanophosphors (RUNPs) is to prepare hydrophilic RUNPs with strong upconverting luminescence. Herein, we developed a simple one-pot synthesis strategy for hydrophilic NaYF4:Yb,Er nanophosphors by hydrothermally treating water/ethylene glycol mixture containing different rare-earth ions, BF4-, Na+ and polyethylene glycol (MW=6000, abbreviated as PEG-6000). NaYF4:Yb,Er sample consisted of irregular spherical nanoparticles with average size of similar to 50 nm, and it could be easily dispersed in water due to the presence of PEG-6000. Importantly, the aqueous dispersion of NaYF4:Yb,Er nanoparticles exhibited bright upconversion luminescence and could be used for imaging HeLa cells. Therefore, these hydrophilic NaYF4:Yb,Er nanoparticles have great potential as luminescent labeling materials for biological applications. (C) 2014 Elsevier By. All rights reserved.
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