期刊
IEEE TRANSACTIONS ON MEDICAL IMAGING
卷 30, 期 9, 页码 1581-1590出版社
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TMI.2011.2125982
关键词
Angiography; biomedical imaging; magnetic particle imaging; magnetic particles
类别
资金
- California Institute for Regenerative Medicine (CIRM) [T1-00007, RT1-01055-1]
- Siebel Foundation
- University of California Berkeley
- National Institutes of Health
Magnetic particle imaging (MPI) is a promising new medical imaging tracer modality with potential applications in human angiography, cancer imaging, in vivo cell tracking, and inflammation imaging. Here we demonstrate both theoretically and experimentally that multidimensional MPI is a linear shift-invariant imaging system with an analytic point spread function. We also introduce a fast image reconstruction method that obtains the intrinsic MPI image with high signal-to-noise ratio via a simple gridding operation in x-space. We also demonstrate a method to reconstruct large field-of-view (FOV) images using partial FOV scanning, despite the loss of first harmonic image information due to direct feedthrough contamination. We conclude with the first experimental test of multidimensional x-space MPI.
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