期刊
IEEE SENSORS JOURNAL
卷 10, 期 3, 页码 755-759出版社
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/JSEN.2009.2039522
关键词
Terahertz (THz) radiation; absorption signature; nanofluidic channels; RNA
资金
- U.S. Army Research Office
- U.S. Army Edgewood Chemical and Biological Center, Aberdeen, MD
Terahertz (THz) transmission measurements are carried out on double-stranded, small-interfering (si)-RNA (20-25 bp) samples suspended in buffer solution and confined to the channels of a nanofluidic chip having channel dimensions similar to 600 x 500 nm and a pitch of similar to 1.2 mu m. The transmission is measured between 800 and 1090 GHz, using a coherent photomixing spectrometer tuned in 0.5 GHz steps. Five narrow spectral signatures are observed that repeated in two successive experiments. Remarkably, the linewidth of some of these features is approximately 10 GHz, making them comparable to if not narrower than the sharpest signatures ever reported at THz frequencies in the solid or liquid states at room temperature.
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