期刊
LIPIDS IN HEALTH AND DISEASE
卷 14, 期 -, 页码 -出版社
BMC
DOI: 10.1186/1476-511X-14-2
关键词
Irisin; Obesity; Metabolic diseases
资金
- Shanghai Shenkang Prevention Prog of Disease [SHDC12012303]
- Chinese Medical Association Fund [12020 550355]
Irisin is a newly discovered exercise-mediated myokine which regulates energy metabolism and has been the subject of much recent research. Irisin plays an important role in metabolic diseases making it a potential new target to combat obesity and its associated disorders, such as T2DM. However, the results of several recent studies investigating the effects of irisin have been controversial. The present review will introduce the discovery of irisin, the role of irisin in metabolic disorders, possible mechanisms, and unanswered questions for future research.
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