期刊
HYPERTENSION
卷 64, 期 5, 页码 1073-+出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1161/HYPERTENSIONAHA.114.03957
关键词
age group; ambulatory blood pressure monitoring; blood pressure; epidemiology; hypertension
资金
- Liechtenstein Government
- Swiss Heart Foundation
- Swiss Society of Hypertension
- University of Basel
- University Hospital Basel
- Hanela Foundation
- Schiller AG
- Novartis
- Swiss National Science Foundation [PP00P3_133681]
- European Union [HEALTH-2011.2.4.2-2-EU-MASCARA, HEALTH-F7-305507 HOMAGE, LSHM-CT-2006-037093, HEALTH-F4-2007-201550]
- European Union (European Research Council Advanced Researcher Grant) [2011-294713-EPLORE]
- Fonds voor Wetenschappelijk Onderzoek Vlaanderen, Ministry of the Flemish Community, Brussels, Belgium [G.0881.13, G.088013]
- Danish Heart Foundation [01-2-9-9A-22914]
- Lundbeck Fonden [R32-A2740]
- Ministry of Education, Culture, Sports, Science and Technology, Japan [22590767, 22790556, 23249036, 23390171, 23790242]
- Health Labour Sciences Research Grant from the Ministry of Health, Labour and Welfare, Japan [H23-Junkankitou [Seishuu]-Ippan-005]
- Japan Arteriosclerosis Prevention Fund
- Central Miso Research Institute, Tokyo, Japan
- National Natural Science Foundation of China, Beijing, China, and the Shanghai [30871360, 30871081]
- Commission of Science and Technology [07JC14047]
- Commission of Science and Technology (Rising Star program) [06QA14043]
- Commission of Education [07ZZ32]
- Commission of Education (Dawn project)
- Comision Sectorial de Investigacion Cientifica de la Universidad de la Republica (Grant I+D GEFA-HT-UY)
- Agencia Nacional de Innovacion e Investigacion
- Grants-in-Aid for Scientific Research [25253059] Funding Source: KAKEN
Mean daytime ambulatory blood pressure (BP) values are considered to be lower than conventional BP values, but data on this relation among younger individuals <50 years are scarce. Conventional and 24-hour ambulatory BP were measured in 9550 individuals not taking antihypertensive treatment from 13 population-based cohorts. We compared individual differences between daytime ambulatory and conventional BP according to 10-year age categories. Age-specific prevalences of white coat and masked hypertension were calculated. Among individuals aged 18 to 30, 30 to 40, and 40 to 50 years, mean daytime BP was significantly higher than the corresponding conventional BP (6.0, 5.2, and 4.7 mm Hg for systolic; 2.5, 2.7, and 1.7 mm Hg for diastolic BP; all P<0.0001). In individuals aged 60 to 70 and >= 70 years, conventional BP was significantly higher than daytime ambulatory BP (5.0 and 13.0 mm Hg for systolic; 2.0 and 4.2 mm Hg for diastolic BP; all P<0.0001). The prevalence of white coat hypertension exponentially increased from 2.2% to 19.5% from those aged 18 to 30 years to those aged >= 70 years, with little variation between men and women (8.0% versus 6.1%; P=0.0003). Masked hypertension was more prevalent among men (21.1% versus 11.4%; P<0.0001). The age-specific prevalences of masked hypertension were 18.2%, 27.3%, 27.8%, 20.1%, 13.6%, and 10.2% among men and 9.0%, 9.9%, 12.2%, 11.9%, 14.7%, and 12.1% among women. In conclusion, this large collaborative analysis showed that the relation between daytime ambulatory and conventional BP strongly varies by age. These findings may have implications for diagnosing hypertension and its subtypes in clinical practice.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据