期刊
HYBRIDOMA
卷 27, 期 4, 页码 249-258出版社
MARY ANN LIEBERT INC
DOI: 10.1089/hyb.2008.0020
关键词
-
资金
- NIH [R01-DE016905, R01-DE12308, R01-GM51188]
- NCI [P30 CA36727]
- UNMC
Cadherins are synthesized with a signal sequence and a proregion that must be removed for optimal adhesive activity. Mutations that prevent processing of cadherins have been implicated in a number of human diseases; thus understanding their processing is critical. In this study, we produced and characterized a number of monoclonal antibodies against the proregion of the desmosomal cadherin, human desmoglein-2, that will facilitate investigations into the processing of this protein.
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