期刊
HUMAN REPRODUCTION
卷 29, 期 2, 页码 276-278出版社
OXFORD UNIV PRESS
DOI: 10.1093/humrep/det420
关键词
in vitro maturation; ovarian cancer; IVF; fertility preservation; cryopreservation
In vitro maturation (IVM) of immature oocytes retrieved from surgically resected ovaries has been proposed as a method of fertility preservation in ovarian cancer patients undergoing definitive surgery. While there had been several reports of successful derivation of mature oocytes and or embryos, there have been no reports as yet of successful pregnancies. In this case report, we present a pregnancy and live birth from a young patient, with stage IIIC ovarian cancer, who had undergone fertility sparing surgery. The immature oocytes recovered after oophorectomy were fertilized after IVM. The embryos obtained were cryopreserved and later transferred to achieve a singleton healthy pregnancy leading to a live birth.
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