期刊
HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
卷 29, 期 4, 页码 322-329出版社
WILEY
DOI: 10.1002/hup.2406
关键词
driving; on-road; impairment; SDLP; excursions out-of-lane
资金
- Dutch Ministry of Infrastructure and the Environment
- Takeda
- Red Bull
- Aventis
- Cephalon
- GlaxoSmithKline
- Neurocrine
- Pfizer
- Sanofi
- Schering-Plough
- Sepracor
- Somaxon
- Syrex
- TransOral
- Wyeth
- Xenoport
Background The traditional outcome measure of the Dutch on-the-road driving test is the standard deviation of lateral position (SDLP), the weaving of the car. This paper explores whether excursions out-of-lane are a suitable additional outcome measure to index driving impairment. Methods A literature search was conducted to search for driving tests that used both SDLP and excursions out-of-lane as outcome measures. The analyses were limited to studies examining hypnotic drugs because several of these drugs have been shown to produce next-morning sedation. Results Standard deviation of lateral position was more sensitive in demonstrating driving impairment. In fact, solely relying on excursions out-of-lane as outcome measure incorrectly classifies approximately half of impaired drives as unimpaired. The frequency of excursions out-of-lane is determined by the mean lateral position within the right traffic lane. Defining driving impairment as having a Delta SDLP>2.4 cm, half of the impaired driving tests (51.2%, 43/84) failed to produce excursions out-of-lane. Alternatively, 20.9% of driving tests with Delta SDLP<2.4 cm (27/129) had at least one excursion out-of-lane. Conclusions Excursions out-of-lane are neither a suitable measure to demonstrate driving impairment nor is this measure sufficiently sensitive to differentiate adequately between differences in magnitude of driving impairment. Copyright (C) 2014 John Wiley & Sons, Ltd.
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