期刊
HUMAN PATHOLOGY
卷 40, 期 7, 页码 909-917出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.humpath.2009.04.001
关键词
Graft-versus-host disease; Gastrointestinal tract; Stomach; Colon; Apoptosis
类别
Graft-versus-host disease (GVHD), a common complication of hematopoietic stem cell transplantation, is a clinical syndrome that requires synthesis of clinical, laboratory, and histopathologic findings for diagnosis. The gastrointestinal (GI) tract is commonly affected, and pathologists must recognize subtle morphologic alterations in GI mucosal biopsies to make the diagnosis and to rule out other causes of GI dysfunction such as cytomegalovirus infection and drug effects. This review summarizes the histopathologic features of GVHD in the GI tract and outlines recent recommendations for reporting of GI biopsies with suspected GVHD. (C) 2009 Elsevier Inc. All rights reserved.
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