期刊
HUMAN MOLECULAR GENETICS
卷 22, 期 -, 页码 R39-R44出版社
OXFORD UNIV PRESS
DOI: 10.1093/hmg/ddt364
关键词
-
资金
- BRC
- John Fell Fund
- Innovative Medicines Initiative [115439]
- European Union
- EFPIA companies
- Medical Research Council [G0601887] Funding Source: researchfish
- MRC [G0601887] Funding Source: UKRI
Migraine is a prevalent, debilitating and costly disorder with an ongoing unmet medical need. Human genetic studies have provided considerable insights into the molecular underpinnings of this complex brain disorder. Classical linkage studies have revealed the causes of familial hemiplegic migraine, while more recently genome-wide association studies have identified several susceptibility loci for typical migraine. New ways of accessing neurons and other cells directly from patients with migraine through the use of induced pluripotent stem cells offer exciting opportunities to understand the molecular pathogenesis. In conjunction with next generation omics, there are unprecedented opportunities to reveal key molecular players in the disease process and discover new drug targets.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据