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Yohei Iguchi et al.
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Amir Aghajanian et al.
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Paolo Pinton et al.
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Patricia Cassina et al.
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L. Dupuis et al.
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Melanie Gertz et al.
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Paolo Pinton et al.
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Alberto Ferri et al.
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Alsin/Rac1 signaling controls survival and growth of spinal motoneurons
Arnaud Jacquier et al.
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Overloading of stable and exclusion of unstable human superoxide dismutase-1 variants in mitochondria of murine amyotrophic lateral sclerosis models
D Bergemalm et al.
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Sos-mediated activation of rac1 by p66shc
FA Khanday et al.
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Apaf1 mediates apoptosis and mitochondrial damage induced by mutant human SOD1s typical of familial amyotrophic lateral sclerosis
M Cozzolino et al.
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Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis
M Giorgio et al.
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K Kanekura et al.
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GTPases and reactive oxygen species: switches for killing and signaling
E Werner
JOURNAL OF CELL SCIENCE (2004)
Evidence for defective energy homeostasis in amyotrophic lateral sclerosis:: benefit of a high-energy diet in a transgenic mouse
L Dupuis et al.
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Alsin is a Rab5 and Rac1 guanine nucleotide exchange factor
JD Topp et al.
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Up-regulation of mitochondrial uncoupling protein 3 reveals an early muscular metabolic defect in amyotrophic lateral sclerosis
L Dupuis et al.
FASEB JOURNAL (2003)
ALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomes
CMJ Higgins et al.
BMC NEUROSCIENCE (2003)
p120 catenin is required for growth factor-dependent cell motility and scattering in epithelial cells
M Cozzolino et al.
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C Napoli et al.
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Rho GTPases in cell biology
S Etienne-Manneville et al.
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Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice
M Mattiazzi et al.
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Y Yang et al.
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Reconstitution of cyclin D1-associated kinase activity drives terminally differentiated cells into the cell cycle
L Latella et al.
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Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple
FQ Schafer et al.
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Caspase-1 and-3 are Sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis
P Pasinelli et al.
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