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Heather L. Montie et al.
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James A. Nathan et al.
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Sokol V. Todi et al.
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Asian origin for the worldwide-spread mutational event in Machado-Joseph disease
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Monica Joch et al.
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Eyal Avraham et al.
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Betty Lamothe et al.
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Proteasome-independent functions of ubiquitin in endocytosis and signaling
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The ubiquitin ligase itch is auto-ubiquitylated in vivo and in vitro but is protected from degradation by interacting with the deubiquitylating enzyme FAM/USP9X
Rania Mouchantaf et al.
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Ronen Ben-Saadon et al.
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Renu Heir et al.
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Cornelia Hampe et al.
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Diverse effects of pathogenic mutations of parkin that catalyze multiple monoubiquitylation in vitro
N Matsuda et al.
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A genomic and functional inventory of deubiquitinating enzymes
SMB Nijman et al.
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Dopamine covalently modifies and functionally inactivates parkin
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Y Mao et al.
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The solution structure of the Josephin domain of ataxin-3: Structural determinants for molecular recognition
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L Zhong et al.
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KL Lim et al.
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Parkin phosphorylation and modulation of its E3 ubiquitin ligase activity
A Yamamoto et al.
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BRCA1:BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair
JR Morris et al.
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RZ Murray et al.
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MY Li et al.
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YH Chai et al.
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XL Wu et al.
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B Burnett et al.
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A Ciechanover et al.
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Structure and ubiquitin binding of the ubiquitin-interacting motif
RD Fisher et al.
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KM Donaldson et al.
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YC Tsai et al.
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E Sakata et al.
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CK Cemal et al.
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HJ Lin et al.
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K Hofmann et al.
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Y Zhang et al.
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Ataxin-3, the MJD1 gene product, interacts with the two human homologs of yeast DNA repair protein RAD23, HHR23A and HHR23B
GH Wang et al.
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H Shimura et al.
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