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Kinetic analysis of human protein arginine N-methyltransferase 2: formation of monomethyl- and asymmetric dimethyl-arginine residues on histone H4
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SMN deficiency causes tissue-specific perturbations in the repertoire of snRNAs and widespread defects in splicing
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An Assembly Chaperone Collaborates with the SMN Complex to Generate Spliceosomal SnRNPs
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The SMN binding protein Gemin2 is not involved in motor axon outgrowth
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CARM1 promotes adipocyte differentiation by coactivating PPARγ
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Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy
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Neurodevelopmental abnormalities in neurosphere-derived neural stem cells from SMN-depleted mice
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PRMT1 and Btg2 regulates neurite outgrowth of Neuro2a cells
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Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy
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HUMAN MOLECULAR GENETICS (2008)
KH-type splicing regulatory protein interacts with survival motor neuron protein and is misregulated in spinal muscular atrophy
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HUMAN MOLECULAR GENETICS (2008)
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Alternative splicing yields protein arginine methyltransferase 1 isoforms with distinct activity, substrate specificity, and subcellular localization
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QNQKE targeting motif for the SMN-Gemin multiprotein complex in neurons
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Axonal-SMN (a-SMN), a protein isoform of the survival motor neuron gene, is specifically involved in axonogenesis
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The RNA-binding protein HuD binds acetylcholinesterase mRNA in neurons and regulates its expression after axotomy
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The arginine methyltransferase CARM1 regulates the coupling of transcription and mRNA processing
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Smn depletion alters profilin II expression and leads to upregulation of the RhoA/ROCK pathway and defects in neuronal integrity
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Multiprotein complexes of the survival of motor neuron protein SMN with Gemins traffic to neuronal processes and growth cones of motor neurons
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Distinct domains of the spinal muscular atrophy protein SMN are required for targeting to Cajal bodies in mammalian cells
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Design and implementation of bimolecular fluorescence complementation (BiFC) assays for the visualization of protein interactions in living cells
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Immunohistochemical and western analyses of protein arginine N-methyltransferase 3 in the mouse brain
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Tudor domains bind symmetrical dimethylated arginines
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Unrip is a component of SMN complexes active in snRNP assembly
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SMNΔ7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN
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PRMT7, a new protein arginine methyltransferase that synthesizes symmetric dimethylarginine
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Molecular and functional analysis of intragenic SMN1 mutations in patients with spinal muscular atrophy
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HUMAN MUTATION (2005)
AU-rich elements and associated factors: are there unifying principles?
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Detection of novel mutations in the SMN Tudor domain in type ISMA patients
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Loss of CARM1 results in hypomethylation of thymocyte cyclic AMP-regulated phosphoprotein and deregulated early T cell development
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GAP-43 mRNA in growth cones is associated with HuD and ribosomes
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PRMT7 is a member of the protein arginine methyltransferase family with a distinct substrate specificity
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Smn, the spinal muscular atrophy-determining gene product, modulates axon growth and localization of β-actin mRNA in growth cones of motoneurons
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Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding
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Specific protein methylation defects and gene expression perturbations in coactivator-associated arginine methyltransferase 1-deficient mice
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Post-transcriptional regulation of acetylcholinesterase mRNAs in nerve growth factor-treated PC12 cells by the RNA-binding protein HuD
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Symmetrical dimethylarginine methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing
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Nerve growth factor-mediated increases in protein methylation occur predominantly at type I arginine methylation sites and involve protein arginine methyltransferase 1
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JOURNAL OF NEUROSCIENCE RESEARCH (2002)
The coactivator-associated arginine methyltransferase is necessary for muscle differentiation - CARM1 coactivates myocyte enhancer factor-2
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
HuD, a neuronal-specific RNA-binding protein, increases the in vivo stability of MYCN RNA
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
A predominantly nuclear protein affecting cytoplasmic localization of β-actin mRNA in fibroblasts and neurons
W Gu et al.
JOURNAL OF CELL BIOLOGY (2002)
Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons?
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Symmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B′ and the Sm-like protein LSm4, and their interaction with the SMN protein
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Overexpression of HuD, but not of its truncated form HuD I+II, promotes GAP-43 gene expression and neurite outgrowth in PC12 cells in the absence of nerve growth factor
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Subcellular localization and axonal transport of the survival motor neuron (SMN) protein in the developing rat spinal cord
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